MGH Appointment: Biostatistician, Department of Neurology
HMS Appointment:
MGH Address: Office at MIT, Department of Brain and Cognitive Sciences, NE20-352, Cambridge, MA 02139
MGH
Phone Number: (AT MIT) 617-253-8976
E-Mail Address: JOMIT@MIT.EDU
Fax Number: 617-253-1504
Undergraduate Education: B.S., Loyola University of Chicago
Graduate and/or Medical School: M.A., Clinical Psychology, University of Kansas; Ph.D., Psychology (Statistics, Methodology) Northwestern University, Evanston, IL
Residencies and Fellowships:
Foreign Language Spoken:
Certification by an American Specialty Board:
Primary Specialty: Statistics
Other Specialties: Clinical Psychology
Research Interests: Alzheimer's disease, Parkinson's disease, Data Analysis Methods
Clinical Interests: Representative Publications:
Locascio, J.J. The cross-lagged correlation technique: reconsideration in terms of exploratory utility, assumption specification and robustness. Educational and Psychological Measurement, 1982, 42, 1023-1036.
Locascio, J.J. and Cordray, D.S. A reanalysis of "Lord's paradox." Educational and Psychological Measurement, 1983, 43, 115-126. Locascio, J.J. A secondary analysis of a major societal experiment on the effects of standardized testing in elementary schools. Evaluation Review, 1984, 8(2), 141-166.
Locascio, J.J., Lee, J. and Meltzer, H.Y. The importance of adjusting for correlated concomitant variables in psychiatric research. Psychiatry Research, 1988, 23, 311-327.
Locascio, J.J., Malone, R.P., Small, A.M., Kafantaris, V., Ernst,M., Lynch, N.S., Overall, J.E. and Campbell, M. Factors related to Haloperidol response and dyskinesias in autistic children. Psychopharmacololgy Bulletin, 1991, 27(2), 119-126.
Locascio, J.J., Growdon, J.H. and Corkin, S. Cognitive test performance in detecting, staging, and tracking Alzheimer's disease. Archives of Neurology , 1995, 52, 1087-1099.
Growdon, J.H., Locascio, J.J, Corkin, S., Gomez-Isla, T., and Hyman, B.T. Apolipoprotein E Genotype does not influence rates of cognitive decline in Alzheimer's disease. Neurology, 1996, 47, 444-448.
Gomez-Isla, T., West, H.L., Rebeck, G.W. Harr, S.D. Growdon, J.H., Locascio,J.J., Perls, T.T., Lipsitz, L.A., and Hyman, B.T.. Clinical and pathological correlates of Apolipoprotein E e4 in Alzheimer disease. Annals of Neurology, 1996, 39, 62-70.
Locascio, J. J., Jennings, P.J., Moore, C.I., and Corkin, S. Time series analysis in the time domain and resampling methods for studies of functional magnetic resonance brain imaging. Human Brain Mapping, 1997, 5(3), 168-193. Locascio, J. J. Significance tests and "results-blindness". American Psychological Association (APA) Monitor, May, 1999, pg. 11.
Rebeck GW, Cheung BS, Growdon WB, Deng A, Akuthota P, Locascio J, Greenberg SM, and Hyman BT. Lack of independent associations of APOE promoter and intron 1 polymorphisms with Alzheimer's disease. Neuroscience Letters, 1999, 272:155-158.
Binetti, G., Locascio, J.J., Corkin, S., Vonsattel, J.P., and Growdon, J.H. Pick's disease differs from Alzheimer's disease in clinical presentation and rate of cognitive decline. Archives of Neurology, in press.