Name:  Oksana Berezovska, Ph.D.

MGH Appointment: Assistant in Neurology 
HMS Appointment: Instructor in Neurobiology 
MGH Address: CNY, 114-16th, Rm. 2750 
MGH Phone Number: 6-1263 
E-Mail Address: oberezovska@partners.org 
FAX Number: 4-1480 
Undergraduate Education: Kiev University, Kiev, Ukraine 
Graduate and/or Medical School: Bogomoletz Institute of Physiology, Ukrainian Academy of 
Sciences Residencies and Fellowships: Saskatchewan University, Canada; 
Mass General Hospital, Boston, MA 
Foreign Language Spoken: Ukrainian, Russian 
Primary Specialty: Neuroscience 
Other Specialties: Cell Biology 
Research Interests: Neurodegenerative disorders 

Representative Publications: 
Berezovska O ., Ramdya P., Wolfe M.S., Bacskai BJ., Hyman BT. 
APP associates with a Nicastrin dependent docking site on the PS1/-secretase 
complex in cells demonstrated by Fluorescence Lifetime Imaging. 
J. Neurosci., 2003 , 23(11), 4560-4566.    

Berezovska O ., Jack C, Deng A, Gastineau N, Rebeck GW, Hyman BT. 
Notch1 and amyloid precursor protein are competitive substrates 
for presenilin 1-dependent {gamma}-secretase cleavage. 
J. Biol. Chem., 2001, v276, (32), 30018-30023. 
 
Berezovska O ., Jack C., McLean P., Aster J., Hicks C., Xia W., Wolfe MS., 
Kimberly WT., Weinmaster G., Selkoe DJ., Hyman BT. Aspartate mutations in presenilin and 
g-secretase inhibitors both impair Notch1 proteolysis and nuclear translocation with 
relative preservation of Notch1 signaling. J.Neurochem., 2000 , v75 (2), 583-593. 

John Lester (lester@helix.mgh.harvard.edu).